Optimus Prime
Frank Welker or Hugo Weaving?
I assume Frank Welker is the original voice actor. As I’ve never cared about Transformers, Hugo Weaving, then.
Mr. Pink or Mr. White?
Strangely enough, neither have I.
Gosh that’s hard. Mr. Pink. I love Buscemi just bit more than Keitel.
Vic or Vince?
Vincent.
Vincent or Jules?
Jules
Mia or Beatrix?
Difficult, as I dislike Uma. But I think I prefer Beatrix. Yes, I prefer Beatrix a lot.
Melanie Laurent or Diane Kruger?
Melanie. Not to say that I don’t care for Kruger, it’s just that Melanie had the more captivating performance in the film. And the only other thing I’ve seen Kruger in is Cage’s peripheral love interest in the Treasure franchise
Pitt or Waltz?
The question, the question.
The Riddler or The Penguin?
Question is in there. But I admit I edited in there at the last second, just before you posted. So you may have been on at the same time and missed it.
Riddler
Waltz, but for that one part, as I haven’t seen him an anything else. I know that Pitt, on the other hand, is very versatile.
There Will Be Blood or No Country For Old Men?
No Country For Old Men. But that’s only because I haven’t finished TWBB. I lost track of it in the move. If it weren’t for that it would be a nearly impossible call.
Javier Bardem or Josh Brolin?
Brolin. Bardem is an excellent actor, but I can’t stand him as a person.
District 9 or Avatar?
Despite thinking both movies were incredibly overrated and overhyped, I’m going to have to go with D9. For having more substance to its story, better acting and if we go on a budget basis, superior special effects.
Sharlto Copley or Zoe Saldana?
Saldana. I dislike Avatar, but I like her on The Curse of the Black Pearl and specially Star Trek.
Kirk or Spock?
Spock. He just interests me more.
Dead Man’s Chest or At World’s End?
Dead Man’s Chest. I was about to make that one 
Davy Jones or Barbossa?
Barbossa. Just had a certain charisma about him. Though I love both characters a lot.
Ian McShane or Penelope Cruz?
I gotta admit I don’t remember McShane’s previous work. But I expect a lot from him.
Yes, Barbossa is the most charismatic character ever, isn’t he?
The Black Pearl or The Flying Dutchman?
The Black Pearl. As much as I love the eerie supernatural design for the Flying Dutchman, I’m always going to tip my hat to the more classic ride.
Jack Davenport or Tom Hollander?
Davenport. But I also liked Hollander’s Beckett.
Pintel or Ragetti?